Is the Brain Responsive to Certain Proclivities?

I just want people to understand what we can and can't get from neuroscience. People have this weird idea that if you're saying that certain proclivities, let's say, would urge people to one side or the other, that you're somehow essentializing things, and you're not. I think about this a lot. Why do some brains end up with this heightened threat response? And I feel like this is one area where physiology and sociology can help. It has everything to do with the mother breathe polluted air while she was pregnant. How was the prenatal care? How was postnatal care? All these things affect the brain's proclivities that it emerges into the world with.