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The CLL Sessions: frontline therapy, BTK inhibitors, MRD negativity & novel therapies

VJHemOnc Podcast

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Update on CLL14 Trial

This chapter discusses the update of the CLL14 trial, comparing Venetoclase plus Ovenituzumab to Klumusia plus Ovenituzumab and highlighting better outcomes with Venetoclase plus Ovenituzumab. It also examines the impact of PFAS therapy in patients with TB53 mutation or deletion. The speakers express concern about the progression in unmutated IGBH patients and raise questions about the depth of remission and the duration of therapy for higher-risk patients.

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