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#56 - Muscle plasticity, aging and exercise with Dr Benjamin Miller
Inside Exercise
The Importance of My Own Nuclei in Muscle Biopsies
In muscle fiber myofibers are multi nucleated and we've known that for, you know, that's a one of the cool things about muscle I guess it's because it's such a large cell fiber. Each fiber of those 572 my muscle biopsies would have more than one nucleus. So they're stuck in this G zero phase of the cell cycle so they exit the cell cycle after development they stuck in G zero. And what we found when we did that study is that myuclei were replicating their DNA. That goes against the dogma that they're stuck on this non-mitotic state. What I think is happening is something called endo replication where you
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