3min chapter

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#216 – Vincent Racaniello: Viruses and Vaccines

Lex Fridman Podcast

CHAPTER

Aren't Structural Biologists Going to Get Giddy?

The ultimate goal of getting a structure is that then you can do experiments and figure out what the structure means, right? So many, in the old days, structural biology was a career in itself. You didn't really do any experiments. Now young structural biologists are multifaceted. They solve the structure and then they say, what happens if we change this amino acid? Oh, look, it blocks binding to the receptor. This must be the receptor binding interface. That's the exciting stuff. Absolutely is doing the experiment. I wonder if you can simulate almost evolution in that way for primitive biological systems. Some of them in simulation fight each other and then see what comes out like a super

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