Evaluating Hypertonic Saline in Trauma Care

This chapter explores the use of 7.5% hypertonic saline in low-volume resuscitation, tracing its historical development and mixed clinical results. It emphasizes the complexities of its application in hemorrhagic shock and traumatic brain injury, discussing the necessity of blood transfusions and the challenges of patient enrollment in related studies. The chapter calls for further research to clarify the optimal use and dosing of hypertonic saline, addressing existing misconceptions and the impact on patient outcomes.