17: Is it important to reverse to a train-of-four target of 90%? - Part 2 of 2
Depth of Anesthesia
The Effects of Paralysis on Pharyngeal Function
The train of four ratio is the figure I often hear quoted today. It's really just looking at one small range across a much larger spectrum of neuromuscular and blockade. We just happen to be blind until we have enough blocked that we start to see a decrease in train of 4 ratio. But you have to have 80% of your acetylcholine receptors blocked before you see the first decrease in train Of Four Ratio.
In this part II or II series on neuromuscular blockade, we investigate the claim that a train-of-four target of 90% is important to achieve prior to extubation.
Our guest today is Dr. Daniel Saddawi-Konefka, residency program director at Mass General.
Connect with us @DepthAnesthesia on Twitter or email us at depthofanesthesia@gmail.com.
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Music by Stephen Campbell, MD.
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References
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Section Editor(s): Brull, Sorin J.Murphy, Glenn S. MD; Szokol, Joseph W. MD; Marymont, Jesse H. MD; Greenberg, Steven B. MD; Avram, Michael J. PhD; Vender, Jeffery S. MD Residual Neuromuscular Blockade and Critical Respiratory Events in the Postanesthesia Care Unit, Anesthesia & Analgesia: July 2008 - Volume 107 - Issue 1 - p 130-137 doi: 10.1213/ane.0b013e31816d1268
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