End of the vincristine/steroid pulse era in pediatric ALL?, “trial and error” with abatacept in GVHD, and hemorrhage risk with dasatinib therapy
Blood Podcast
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The Effects of Disatinib on Platelet Migration
In disatinib phase 1 and 2 studies, nearly one quarter of patients had drug-associated hemorrhage. In more than 80% of cases, the bleeding was gastrointestinal or mucosal. Platelets from patients treated with bosutinib exhibited a striking reduction in capacity to migrate.
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