The Endocannabinoid System Is Very Important in All of This

The endocannabinoid system is this regulatory framework around your energy metabolism. When you eat excess linoleic acid, you generate a signal that tells your brain that you don't have enough fuel. And it makes you eat more, right? Don't eat. This has been demonstrated so many times in mice, it's not even worth going through the studies. THC gives you the munchies and it's used as a drug, an FDA approved drug called dronabenol to treat people with cancer and AIDS who don't want to eat because it makes them eat. The SCD1 knockout mouse model shows how altering these elements of the system can control obesity or leanness.