Heat therapy, exercise and chronic disease with Dr Paige Geiger
Inside Exercise
Heat Therapy and Insulin Resistance in Rats
Exploring a study on rats where a weekly hot water bath counteracts insulin resistance caused by a high-fat diet, along with comparisons to human behavior and extreme rodent studies.
Dr Glenn McConell chats with Professor Paige Geiger from the University of Kansas Medical Centre on Heat therapy, exercise and chronic disease. Paige has undertaken very important mechanistic and allied work in this field. We discussed many things (see time stamps below).
0:00. Introduction how got into the area
6:26. How first idea to look at heat and diabetes Phil Hooper in 1999 put people with T2D in hot tubs
9:00. Heat shock proteins (HSPs) Activated by many stresses in addition to heat. Many roles.
10:53. High fat diets and heat Need to raise body temp by 1C
14:22. Body temp increases during exercise Some of the benefits/adaptations from exercise may be activation of HSPs
16:26. Preconditioning and HSPs
17:49. Separating the effects of exercise from heat Additive effect of exercise and heat?
20:54. Q10 effect, exercise and HSPs?
22:27. HSPs with heat vs exercise
25:54. Ideal heat therapy dose Temperature, time, number of sessions.
29:55. Why not just exercise? Not everyone can exercise.
32:22. Heat therapy for chronic diseases 35:08. Sauna vs hot tub 36:58. Higher core temp vs heating muscle
38:40. Heat and myokines/exosomes 40:33. What’s turning on HSPs Heat shock factor 1 etc.
43:52. Heat therapy and the mitochondria/insulin sensitivity
49:35. How often need heat therapy?
51:34. Does everyone respond to heat?
52:45. Is heat therapy appropriate for all?
54:13. Aging and heat therapy 55:23. Heat having effects in addition to HSPs?
56:49. Troubleshooting in the lab
59:14. HSPs, exercise and the liver
1:01:56. Too much comfort?
Inside Exercise brings to you the who's who of exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).
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