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Pyruvate Dehydrogenase | MWM Energy Metabolism Cliff Notes #13

Mastering Nutrition

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Enzyme Similarities and Thiamine Requirement in Energy Metabolism

The chapter discusses the similarities between enzymes involved in pyruvate dehydrogenase and alpha-ketoglutarate complexes, highlighting the crucial role played by dihydrolipoyl dehydrogenase in transferring hydrogen ions and electrons. It also explores vulnerabilities to oxidative stress and heavy metal toxicity, emphasizing the importance of thiamine in carbohydrate metabolism.

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