The Role of Sirt Proteins in Caloric Restriction and Exercise

This chapter explores the localization and functions of different types of Sirt proteins in relation to caloric restriction and exercise. It discusses how Sirt proteins react to redox state and amplifies the signal to take action. The chapter also highlights the importance of measuring certain aspects of cellular health, such as NADH levels, and discusses studies conducted on rodents and humans to understand the effects of exercise on enzyme activity and nuclear function.