4min chapter

The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence) cover image

Explainable AI for Biology and Medicine with Su-In Lee - #642

The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)

CHAPTER

The Importance of Flexibility in Computational Biology Methods

In all computational biology methods, it's really important not to make it too rigid for the existing knowledge. It needs to be flexible. So in this particular example, we didn't use a pathway actually from the beginning. When the model training happens, we used genes as individual features. And then we analyzed the feature attributions and then did the statistical test to see which pathways seem to be more activated.

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