5min chapter

The Curbsiders Internal Medicine Podcast cover image

#380 Hemochromatosis with Elliot Tapper

The Curbsiders Internal Medicine Podcast

CHAPTER

Is There a Differential Diagnosis for an Elevated Ferritin?

The two critical indices are one ferritin, which is going to be elevated and two transferrin saturation. Once you get those numbers, if it's greater than 45%, you start to worry about hemochromatosis. When I look at the CBC and the liver enzymes, I'm mainly using this to start calculating in my mind the probability of cirrhosis. Is the AST greater than the ALT has the Play the Count drop below 150 below 100? It helps me prioritize how important it is to come up with a firm diagnosis for them as well.

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