
REBEL Core Cast 142.0–Ventilators Part 2: Simplifying Mechanical Ventilation – Most Common Ventilator Modes
REBEL Cast
Other Modes: Volume Support and APRV Mention
Introduces volume support as a spontaneous PRVC-like mode and references APRV and additional Rebel EM resources for deeper dives.
		🧭 REBEL Rundown
🗝️ Key Points
- 💨 Start with Breath Types: Controlled, assisted, and supported breaths are the foundation of all modes.
 - 🛌 Comfort Over “Best Mode”: No mode improves mortality — focus on patient synchrony and comfort.
 
 Know the Big 5 Modes: AC: All controlled or assisted (volume or pressure). PS: Fully spontaneous, great for SBTs. PRVC: Pressure-delivered, volume-targeted hybrid. SIMV: Mixed mode, less favored in adults. VS: Spontaneous mode with adaptive pressure.- ⚠️ Watch for Pitfalls: PRVC may under-ventilate in agitation. SIMV often causes dyssynchrony.
 - 🎯 Bottom Line: Master mode mechanics and match the vent to the patient — not the other way around.
 
📝 Introduction
Mechanical ventilation can feel overwhelming, especially when faced with a sea of ventilator modes and unfamiliar terminology. In Part 2 of the series, we go beyond breath types and delivery mechanics to explore the most used modes in the ICU. We will break down each one; explaining how it works, when to use it, and why the goal isn’t the “best mode” but the most comfortable one for the patient.
️ Ventilator Modes Explained
				
 Assist Control (AC)
- Commonly mislabeled as “volume control” or “pressure control.”
 - Two main types:
- AC Volume: Delivers a preset tidal volume with each breath, whether machine-initiated (controlled) or patient-initiated (assisted).
 - AC Pressure: Delivers a preset pressure; tidal volume varies based on compliance.
 
 - All breaths are either controlled or assisted.
 
 Pressure Support (PS)
- All breaths are spontaneous initiated by the patient.
 - The ventilator provides a preset level of pressure support, like a resistance band during a pull-up.
 - No set rate, but a backup mode (often AC) activates during apnea.
 - Commonly used for spontaneous breathing trials (SBTs) to assess extubation readiness.
- Typical goal: Patient breathing comfortably with PS ~5 cmH₂O and reasonable rate.
 
 
 Pressure Regulated Volume Control (PRVC)
- Also called autoflow or adaptive pressure ventilation.
 - A hybrid mode: Pressure-delivered, volume-targeted.
 - Delivers breaths with a decelerating flow waveform, mimicking physiologic breathing.
 - Adjusts pressure breath-to-breath to meet a target tidal volume with minimal required pressure.
 - Safety feature: Pressure limit (e.g., 30–35 cm H₂O). If exceeded, volume delivery stops early.
 - Pitfall: In agitated patients, rapid breathing may trick the ventilator into reducing pressure, causing under-ventilation.
 
 Synchronized Intermittent Mandatory Ventilation (SIMV)
- Less common in adult ICU but still commonly used in pediatrics.
 - Delivers a set number of mandatory (controlled or assisted) breaths.
 - Allows spontaneous, pressure-supported breaths between mandatory ones.
 - Example: SIMV 10 = 10 guaranteed AC breaths; additional breaths are spontaneous + supported.
 - Why it’s less popular: Found to be less effective than daily SBTs for weaning and frequent dyssynchrony from not giving enough PS (PS should target at least 2/3 of the AC breath volumes) .
 
 Volume Support (VS)
- A newer, fully spontaneous mode (like PS + PRVC).
 - Patient initiates all breaths.
 - The ventilator automatically adjusts pressure support to achieve a target tidal volume.
 - Think of it as the spontaneous cousin of PRVC—adaptive and volume-driven.
 
🚨 Clinical Bottom Line
Understanding ventilator modes starts with knowing breath types, delivery mechanics, and clinical goals. When it comes to choosing the right mode:
- Focus less on the “best” mode and more on patient comfort and synchrony.
 - Recognize the strengths, limitations, and pitfalls of each mode.
 - Stay tuned for future episodes that dive into ventilator troubleshooting and advanced respiratory strategies.
 
Post Peer Reviewed By: Marco Propersi, DO (Twitter/X: @Marco_propersi), and Mark Ramzy, DO (X: @MRamzyDO)
Show Notes By: Nicole Ebalo, DO
👤 Guest Contributors
																	Eric Acker, MD
																	Nicole Ebalo, DO
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