The most common reason that s s aris don't work is because there is another thing going on. If i start someone who has an alcohol problem on an ssari or anti depressent medication, that may help some. But the alcohol itself, if i'm drinking every day, that's going to cause depression. The other thing that we know is that when people are alcoholic and they have an untreated depression, that can make it hard to become sober. So for people who hae multiple diagnoses, i would be super careful about thinking something quatern quote, doesn't work.