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Immune Thrombotic Thrombocytopenic Purpera (iTTP)

JAMA Clinical Reviews

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Understanding iTTP: Diagnosis and Treatment

This chapter explores the diagnostic process for Immune Thrombotic Thrombocytopenic Purpura (iTTP), highlighting the significance of the ADAMTS-13 enzyme and the role of various diagnostic tools like the PLASMIC scoring system. It further discusses treatment options, including therapeutic plasma exchange and immunosuppressive therapies, emphasizing the urgency of prompt action in managing this rare but critical condition.

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