October 2024 Recall: Approaches To Clinical Diagnosis of Parkinsonism
Neurology® Podcast
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Advancing Diagnostics in Synucleinopathies
This chapter reviews the development of skin biopsy testing for phosphorylated alpha-synuclein as a diagnostic tool for synucleinopathies like Parkinson's disease. It discusses a large study that demonstrated over 95% sensitivity in detecting this biomarker among patients diagnosed with these neurodegenerative disorders. The speakers also emphasize the importance of accurate diagnosis through multiple biopsy sites and the implications of their findings for clinical practice.
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