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Ep. 97: “Viral Structures” Featuring Dr. Erica Saphire

The Immunology Podcast

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Unraveling ILC2s: The New Frontier in Pancreatic Regulation

This chapter delves into the concept of immune cell 'exhaustion', proposing 'moderation' as a more fitting term, and emphasizes the critical role of ILC2s in regulating glucagon and glucose levels in the pancreas. It highlights recent findings on the surprising presence of ILC2s during fasting and their interaction with the nervous system through adrenergic signaling. The discussion intricately weaves together the signaling pathways and evolutionary aspects of these immune cells, revealing their unexpected contributions to metabolic processes.

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