Cellular Effects of Chronic Stress

Learn why uncertainty fuels anxiety and how noticing our body’s stress signals can help us find calm.

Summary: One in five adults in the U.S. report living with anxiety, and many of us struggle to control or avoid the feelings that come with it. Science shows that tuning into the body, rather than resisting discomfort, can actually reduce anxiety and strengthen resilience. Join us on The Science of Happiness as we explore what anxiety teaches us about control, uncertainty, and how to care for ourselves with more compassion.

How To Do This Practice:

1. Create a quiet moment for yourself: Find a space where you won’t be interrupted—even just for 30 seconds. Close the door, silence your phone, and step away from distractions.
2. Take a deep breath in: Begin with one slow, steady inhale. On the exhale, let your body soften. Keep your breathing gentle, not forced.
3. Do a quick scan: Where are you holding stress? Maybe in your chest, shoulders, or jaw. Simply notice the tightness or pressure without trying to change it.
4. Breathe into those sensations: With each inhale, imagine sending your breath to the place where stress lives in your body. With each exhale, release a little of that tension—like letting it flow out.
5. Name what’s on your mind: Ask yourself: What am I feeling? Am I anxious about the past, worried about the future, or caught up in uncertainty? You don’t need to solve or fix anything—just acknowledge it.
6. Let it go, even briefly: Tell yourself, I don’t have to fix this right now. Allow the stress to soften as you exhale. Even 20–30 seconds can bring a sense of calm and clarity.

Scroll down for a transcription of this episode.

Today’s Guests: 

JENNY LITTLE is a Health and Fitness Director at the Albany YMCA.

DR. ELISSA EPEL is a psychologist and professor at UCSF. Her research shows how chronic stress and anxiety affect our bodies at the cellular level.
Learn more about Dr. Elissa Epel here: https://www.elissaepel.com/

Related The Science of Happiness episodes:  

How Holding Yourself Can Reduce Stress: https://tinyurl.com/2hvhkwe6
Hot to Tap Your Way to Calm and Clarity: https://tinyurl.com/psmskjyp
How To Tune Out The Noise: https://tinyurl.com/4hhekjuh

Related Happiness Breaks:

Make Uncertainty Part of the Process: https://tinyurl.com/234u5ds7
A Meditation for When You Feel Uneasy: https://tinyurl.com/4x27ut3p
A Meditation For When You Have Too Much To Do: https://tinyurl.com/5dvk3d7m

Tell us about your experience with this practice. Email us at happinesspod@berkeley.edu or follow on Instagram @HappinessPod.

Help us share The Science of Happiness! Leave us a 5-star review on Apple Podcasts and share this link with someone who might like the show: https://tinyurl.com/2p9h5aap

Transcription: https://tinyurl.com/mskvfmv4