The Official Fasting Q&A With Ben Greenfield: Does Coffee Break Your Fast, Poor Sleep During Fasting, Amino Acids During Fasting & Much More!
Boundless Life
The Effects of Fasting on Autophagy
MTOR is an enzyme in terms of mechanistic or mammalian. It manages the processes that generate or use a large amount of energy, like cell growth or protein synthesis and autophagy. When mTOR is activated, autophagy is suppressed; when mTOR isn't activated, it increases. Research has shown over and over again that fasting reduces mTOR activation. And then there's this idea of ketosis, which occurs when your body utilizes fat to burn fuel.
The recent Kion 5 Day Fast has now come to a close - and we had over 10,000 people participate (that's a whole lot of food that wasn't eaten).
During the fast, I received plenty of questions about fasting, such as:
Does coffee help or harm your fast?
What can I do to improve my sleep during - and after - a fast?
What is the hormonal effect of fasting on males? And what about for women?
What is the best kind of fasting if your goal is body composition (fat loss, muscle gain/maintenance)?
Does fasting - especially 3-5 day extended fasts - slow down your metabolism?
What type of training is best while fasting, and what type of training should be avoided?
What other things can you do to enhance the benefits of a fast? (e.g. cryotherapy, enemas, etc.)
How should you prepare for - and break - an extended fast?
Is it OK to fast while breastfeeding or pregnant?
Does your ability to absorb food and supplements increase after a fast?
What are your thoughts on EAAs while fasting? Do they break a fast? And what about BCAAs?
And many more!
So in today's episode, I dive into an official fasting Q&A solosode. Enjoy! Here are the questions I'll be answering: -How does fasting for longevity differ from fasting for things like fat loss or circadian rhythm...7:45- Decreasing calorie intake 20-40% is most optimal way to regulate aging and increase life span
- Inhibit mTOR pathway, stimulate autophagy, induce ketogenesis
- Autophagy: "self eating" - not to be confused with apoptosis, which is cell death
- Autophagosomes to lysosomes "spring cleaning in your cells"
- Eating shuts down autophagy; fasting increases autophagy
- mTOR: mammalian target of rapamycin
- Energy enzyme
- ATP becomes ADP
- Every time you eat, you activate mTOR and suppress autophagy
- Ketosis: using fat as the primary source of fuel
- Less oxidative stress; slows the aging process
- My personal protocol:
- 12-16 hour intermittent fast daily
- 24 hour fast (dinner to dinner) twice a month
- Fasting mimicking diet (FMD) 4x/year
- Black coffee can enhance fatty acid mobilization from adipose tissue, alertness, metabolism,
- Coffee without any calories added (coconut oil, butter, etc.) will help the fast
- Carb intake at night (dinner time) assists with sleep
- Shut down the sympathetic nervous system to get to sleep while fasting
- You can get by on less sleep when you're fasting
- Don't forget the efficacy of breath work and meditation
- Lean and fit females do better with shorter fasts (12 hours); men are more versatile
- Insulin, growth hormone, responds favorably to a fast
- Noradrenaline increases with fasting
- Level of testosterone increase while fasting is unknown
- Podcast on kisspeptin
- Berberine
- Bitter melon extract
- Rock lotus extract
- Kion Lean
- Sauna sessions
- Cold thermogenesis
- Podcast on liver cleanse
- Anything that rapidly depletes glycogen or carb levels will have deleterious effects
- HIIT
- High weight, low reps; body building vs. weight lifting
- Walking, swimming, yoga; something you can do and have a conversation
- When finished with a fast, you'll be less equipped to digest complex meals
- Go low and slow when reintroducing foods
- Soft cook veggies;
- Avocados, grass feed cottage cheese, eggs,
- No steaks; anything you need to chew for a long time
- Peter Attia's "nothing burger"
- Religions encourage women to refrain from fasting while pregnant or breastfeeding
- Biochemical changes in milk in response to fasting
- Think "feast" not "famine"
- Kion Flex
- Masszymes
- Don't use them if your goal is cellular autophagy
- Can be very useful for resetting circadian rhythm, gut cleanup, spiritual benefits, etc.
- Can be a good mTOR activator
- Dry mouth, from amino acids:
- Spilanthes, electric berries
- Ginger, cayenne powder increases salivary production
- GI effects:
-Kion Berry Aminos Building blocks for muscle recovery, reduced cravings, better cognition, immunity, and more. Now in a DELICIOUS berry flavor!
-JOOVV After using the Joovv for close to 2 years, it's the only light therapy device I'd ever recommend. Give it a try: you won't be disappointed. Use my link when you order and get a FREE bonus gift!
-The Christian Gratitude Journal When you introduce conscious, mindful gratitude into your day, positivity will begin to pour into your life – along with all the other scientifically proven physical, mental and spiritual benefits that go along with it.
Do you have questions, thoughts or feedback for me? Leave your comments below and I'll reply!
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