Understanding Water Entry and Wrinkling in Fingertips

This chapter explores the mechanics of how water enters the skin of fingertips, leading to wrinkles, and the role of sweat glands, nervous system, and vasoconstriction in this process. It discusses studies from 1936 and 2003 that examined blood flow changes, electrolyte concentrations, nerve firing, and skin tautness as contributors to the formation of aquagenic wrinkles, with implications for testing peripheral nerve function and conditions such as small fiber neuropathy.