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Brad Marshall, Tucker Goodrich on Obesity Causes, Reductive Stress

David Gornoski

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Is It a Little Acid That's Causing This Buildup of NADH?

Vegetable oils don't produce as much of these reactive oxygen species. And therefore they're not giving you back as much NAD+, for every molecule of fat that's being burned. That is why the vegetable oil, I would argue, is giving us this buildup of NADH in the first place. The fatty acids are simply being shuttled into the mitochondria at a rate that is probably in excess of what we want.

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