Alzheimer's Drugs - What's Next?

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The amyloid hypothesis is the idea that these sticky plaques are actually causing the dementia in Alzheimer's. The laconomab drug is a drug that attaches itself to these plaques and attracts the attention of the immune system, which then clear the protein away. This drug measurably does a good job of removing these plaques. And so what we're learning is then that this mechanism in the brain is a useful one to target even though nothing we've tried before has worked.

The Chinese leader who took over a squabbling party following the Tiananmen Square massacre surprised the world by stifling dissent, overseeing a staggering economic awakening—and occasionally breaking into song. We examine the lessons to be drawn from his legacy. After scores of failures, a new Alzheimer’s treatment shows real promise. And our annual ranking of the world’s most expensive cities.

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