20min chapter

The Peter Attia Drive cover image

#143 - John Ioannidis, M.D., D.Sc.: Why most biomedical research is flawed, and how to improve it

The Peter Attia Drive

CHAPTER

Unmasking Research Reliability

This chapter critiques the validity of published clinical research, highlighting significant flaws and biases that can lead to misleading results. It explores the mathematical methodologies behind these findings and the implications of small study sizes and p-values in biomedical research. The discussion underscores the urgent need for improved guidelines and practices to enhance the reliability of scientific outcomes, particularly in evidence-based medicine.

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