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EULAR 2023 Lupus Highlights

Rheumnow Podcast

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The Effects of Cyclophosphamide on Proteinuria

Egyptian study looked at cyclophosphamide in a good strong dose monthly for six months and compared that with barisitinib, four milligrams. Now they've continued the study out to 12 months, the reporting the six-month study here and the 12-month study will have renal biopsies, the six- month study did not. At 12 weeks there was significant reduction in proteinuria, 70% for the baris itinib group, 43% for the cyclophosphamonia group. Similarly, the secondary endpoints like C3 and SLEEDI2K was in favor of barisitInib over cycloph phosphamide.

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