The Benefits of Tau Therapy for Alzheimer's

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Tau NextGen is a type of prevention trial. Participants will have evidence from blood tests and scans that their brains contain plaques and early signs of tau tangles. There will be about 900 participants in six arms who will receive one of two tau therapies either alone or in combination with lachanamab. The research teams hope that anti-tau treatment will boost lachan amab's modest benefits, creating better conditions for the therapy to work.

Last year, researchers announced that the Alzheimer’s drug lecanemab lowered the amount of amyloid protein plaques associated with the disease in the brains of participants in a clinical trial, and slowed their cognitive decline.

Now, researchers are looking to drug combinations, vaccines and gene therapy to tackle different stages of the disease, as they forge the next generation of treatments for the condition.

This is an audio version of our Feature: Conquering Alzheimer’s: a look at the therapies of the future

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