Imputing ancient genomes to measure inbreeding

Genetic history of dog domestication

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In this episode, researchers explore the impact of domestication on dog genetics and behavior.

In this episode, we cover: •[00:00] Introduction •[01:00] Greger Larson explains how the history of gene flow between dogs and their wild relatives differs from what we know about other domestic species. •[02:38] Audrey Lin finds that low levels of wolf ancestry are found in almost two thirds of dog breeds. •[04:18] Linus Girdland Flink documents evidence of two genetic wolves on a remote Scandinavian island that may have been under human control. •[06:13] Clément Car explores how the mating systems of free-ranging village dogs could provide insight into canine domestication •[07:43] Katia Bougiouri explains how she used a statistical method to improve ancient genomes and what her results reveal about the history of inbreeding in dogs. •[09:21] Lachie Scarsbrook explains how he used museum specimens to reconstruct the history of inbreeding in German Shepherd Dogs. •[11:10] Eleanor Raffan analyzes genetic data and owner-submitted behavioral questionaries from 1,343 golden retrievers. •[12:54] Kathryn Lord finds that genetic testing cannot accurately predict canine behaviors. •[14:25] Final thoughts and conclusion.

About Our Guest: Greger Larson Professor University of Oxford

Audrey Lin Gerstner Postdoctoral Scholar American Museum of Natural History

Linus Girdland Flink Lecturer University of Aberdeen

Clément Car Postdoctoral Researcher University of Gdańsk

Katia Bougiouri Postdoctoral Researcher University of Copenhagen

Lachie Scarsbrook Postdoctoral Researcher University of Oxford, Ludwig Maximilian University of Munich

Eleanor Raffan University Associate Professor University of Cambridge

Kathryn Lord Postdoctoral fellow University of Massachusetts Chan Medical School

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