Navigating the Monkeypox Outbreak

This chapter delves into the U.S. monkeypox outbreak, exploring vaccine preparedness and the complexities of administering the ACAM2000 vaccine, particularly for immunocompromised individuals. Through interviews with medical experts, it compares the outbreak's unique challenges to early HIV days while recognizing the advantages from historical investments in smallpox vaccines. The discussion emphasizes the logistical hurdles in vaccine distribution and public frustration over perceived mismanagement despite prior preparations.