
41 - Of Antibiotics and Soap
The Curious Clinicians
00:00
Serphatic Serpacten and Daptomisin Are Similar in Construction
If you add serfacton to dapto mison in vitro, you see almost immediate loss of anti bacterial activity. Oceso: That is the part that doesn't make sense to me. Why does that happen? Well, so remember that d apto mison has that hydro bic tail that to be able to kill bacteria, it needs to insert into their cellular membranes. And there was a really cool experiment published in the journal of infectious diseases in two thousand five that showed a striking finding. If you combine surfact and daptomison, the surfacta surrounds and like, literally traps the daptosmison molecules. It's essentially what serfacton
Transcript
Play full episode