Intro

Upgrade your biology in 10 minutes with this week’s rundown from Dave Asprey. T

This episode covers:

• Longevity Scores Are Going Mainstream

Elegant Hoopoe’s new clinics are using 56 biomarkers to track biological aging — and early users are reporting up to six years reversed in under two months. Could scoring systems replace reactive healthcare?

Source: Morningstar via PR Newswire — https://www.morningstar.com/news/pr-newswire/20251014ln95054

• AI Heart Scans Spot Trouble Sooner

Hospitals are using machine learning to analyze echocardiograms in real time — making heart diagnostics faster, cheaper, and more accurate, even without top specialists on site.

Source: Crescendo.AI News — https://www.crescendo.ai/news/latest-ai-news-and-updates

• Brain Training That Rebuilds Neurotransmitters

McGill’s INHANCE trial shows that 10 weeks of digital training on BrainHQ doesn’t just improve memory — it chemically rejuvenates acetylcholine pathways. That’s measurable neuroplasticity.

Source: Longevity.Technology — https://longevity.technology/news/brain-training-restores-youth-to-aging-minds/

• HLTH 2025 Unveils Digital Twins & Real-Time Immune Wearables

This year’s HLTH conference put bio-individuality front and center: AI twins that simulate your biology, hormone-tracking wearables, and apps syncing with EMRs to turn raw data into real decisions.

Source: HLTH Official — https://hlth.com/2025event

• One Blood Test, Many Diagnoses

New multi-panel tests rolling out in clinics screen for dozens of diseases from a single draw — boosting compliance, streamlining early detection, and making full-spectrum testing routine.

Source: Instagram Science Updates — https://www.instagram.com/p/DP0oGGTiiT5/

This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. 

Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. 

New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. 

Keywords: longevity score, elegant hoopoe, AI heart scans, brainHQ, acetylcholine, McGill INHANCE trial, HLTH 2025, digital twins, hormone wearables, immune tracking, biological age, multi-panel blood test, early detection, personalized medicine, Dave Asprey, Human Upgrade, biohacking news, health tech, performance medicine, smart diagnostics

Thank you to our sponsors!  

-SKILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off.

-EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.

Resources:  

• Danger Coffee: https://dangercoffee.com/discount/dave15 

• Dave Asprey’s BEYOND Conference: https://beyondconference.com 

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated 

• Upgrade Collective: https://www.ourupgradecollective.com 

• Upgrade Labs: https://upgradelabs.com 

• 40 Years of Zen: https://40yearsofzen.com 

Timestamps: 

0:00 — Introduction

0:18 — Story 1: Elegant Hoopoe Longevity Score

1:26 — Story 2: AI-Assisted Echocardiograms

2:17 — Story 3: Brain HQ Cognitive Training Study

3:03 — Story 4: Digital Twins at HLTH Conference

4:13 — Story 5: Single Vial Blood Testing

5:04 — Five Day Experiment

5:46 — Closing

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