Changing the Resting Membrane Potential

If you do that multiple times in a short period of time, that's called temporal summation. And then while you're there, this is where you then bring in situations where you've injured tissue and you have inflammation. And so now you have within the area a change in the chemical environment. So they're more excited, but not necessarily firing that threshold,. But all you might need to do is you've changed the resting membrane potential.