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The Evolution of Gene Loss in the Mitochondria
Mitochondria are very important for the basics of basic processes of life. Anything that goes wrong with mitochondria is going to contribute to all sorts of other diseases. If we get mutations from our mother in our mitochondrial DNA, our mitochondria can't work that well. Under those circumstances, energy-dependent cells like muscle cells, brain cells will show up as not working well and usually childhood diseases will arise. We'd predict there would be a strong push through selection to come to something more complicated but let's see what we find when we go out to look for it.