
REBEL Core Cast 137.0: A Simple Approach to Sinus Tachycardia
REBEL Cast
Understanding and Addressing Pain-Driven Sinus Tachycardia
This chapter delves into the complexities of diagnosing pain-driven sinus tachycardia, stressing the need to explore underlying factors like hypoxemia, shock, or anemia. The chapter introduces a useful mnemonic to aid practitioners in properly assessing and addressing the root causes of tachycardia.

š§ REBEL Rundown
š Key Points
- 𩺠Sinus Tachycardia = Clinical Clue: Donāt just treat the numberāitās a sign of underlying physiologic stress.
- š§® Oxygen Delivery Equation: HR ā may compensate for ā hemoglobin, Oā sat, or cardiac output. Know: š DOā = CO x Hb x Sat + 0.003(pOā)
- šļø Systematic 8-Point Evaluation: š« Airway/Hypoxia, š¬ļø Breathing , š Circulation, š Drugs,𩸠Erythrocytes (Anemia), š”ļø Fever, š¬ Glucose, š āHoly Cow That Hurtsā
- š§ Think Holistically: Tachycardia isnāt the problemāwhatās causing it is.
- š« Avoid Reflexive Beta Blockers: Donāt suppress a compensatory response before finding the cause.
- š Reassess Frequently: Clinical status can changeāstay vigilant.
š Introduction
Sinus tachycardia is the most prevalent cardiac dysrhythmia in critically ill patients, yet it often receives less attention than it warrants. While the rhythm itself is not inherently dangerous, it serves as a crucial indicator of underlying physiological disturbances that require prompt evaluation and management.
š Key Concepts
- Sinus Tachycardia as a Clinical Sign: Rather than focusing solely on the elevated heart rate, clinicians should interpret sinus tachycardia as a symptom pointing toward an underlying cause that needs to be identified and addressed.
- Oxygen Delivery Equation: Understanding the components of oxygen deliveryāhemoglobin concentration, oxygen saturation, and cardiac outputāis essential. An increase in heart rate may be a compensatory mechanism to maintain adequate oxygen delivery when other components are compromised.

8 Causes of Sinus Tachycardia
- Airway/Hypoxia: Ensure the airway is patent and assess for hypoxemia.
- Breathing: Evaluate for respiratory distress or pulmonary pathology.
- Circulation: Consider shock states, including hypovolemia, hemorrhage, or distributive shock.
- Drugs: Review medications and substances that may cause tachycardia, including stimulants and withdrawal states.
- Erythrocytes (Anemia): Assess for low hemoglobin levels that may impair oxygen delivery.
- Fever: Recognize that fever increases metabolic demand, leading to tachycardia.
- Glucose: Identify hypoglycemia or hyperglycemia as potential contributors.
- Holy Cow That Hurts: (Pain/Anxiety): Acknowledge that pain and emotional distress can elevate heart rate.
š Practical Bedside Approach
- Holistic Assessment: Always interpret sinus tachycardia within the broader clinical context.
- Avoid Reflexive Treatment: Refrain from immediately administering rate-controlling medications without identifying and managing the underlying cause.
- Continuous Monitoring: Regularly reassess the patientās status, as the underlying cause of tachycardia may evolve over time.
šØ Clinical Bottom Line
Sinus tachycardia is a vital clinical sign that necessitates a thorough and systematic evaluation to uncover and treat the root cause. By adopting this structured approach, clinicians can improve patient outcomes and avoid the pitfalls of symptomatic treatment without addressing underlying issues.
Post Peer Reviewed By: Marco Propersi, DO (Twitter/X: @Marco_propersi), and Mark Ramzy, DO (X: @MRamzyDO)
š¤ Guest Contributors

Eric Acker, MD

Thirumala āKeerthiā Kammaripalle, MD
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