AMA Question: Where Has Your Opinion Changed?

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There's always going to be that small group of people who are like, why is your opinion changed? How can you speak about something now and this way and then change it? Even the best experiments don't produce certainty. In that sense, there really isn't much that's black and white in science. Most things are shades of gray. Some things are really, really dark shades of gray"

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In this “Ask Me Anything” (AMA) episode, Peter answers a number of questions on optimizing sleep. He describes his pre-bedtime routine, how he utilizes a sauna, and his current regimen of medicines and supplements for improving sleep time and quality. He goes in depth on each of the molecules that have shown promise in boosting sleep, including their mechanisms of action as well as any noteworthy contraindications. Peter also discusses sleep wearables, including both the positives and potential negatives of using such trackers, and much more.

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We discuss:

Peter’s current pre-bedtime routine [3:30];
Sauna: Peter’s routine, sleep benefits, and tradeoffs [10:45];
Importance of keeping an open mind as new information arrives [16:15];
Importance of reducing stimulation leading up to bedtime [19:30];
Medications that can enhance sleep: mechanisms of action, contraindications, risks, and Peter’s regimen [20:30];
Why medications can enhance sleep, but should not replace good sleep habits [34:45];
Sleep supplements: mechanisms of action, contraindications, and Peter’s regimen [37:30];
Temperature during sleep, cooling devices, mattresses, and more [53:00];
A tip to help avoid straining your back in the morning [59:15];
Contrasting polysomnography with wearable sleep trackers [1:00:45];
Sleep tracking wearables: interpreting metrics, and the pros and cons of trackers [1:04:30];
Final takeaways on sleep [1:16:30]; and
More.