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The Pertussis Vaccine
Aluminum hydroxide is used in the pertussis vaccine, which stimulates macrophages to do better at their jobs. This new and improved whole cell pertussisvaccine with this adjuvant was put to the test in 1943. And it was shown to be super successful, provided lasting and effective protection against the disease. In order to reduce the number of shots that children would have to get for vaccines, the pertussedis vaccine was combined with ones for diphtheria and tetanus in the mid 1940s.