The Role of Eye Toxicity in CNS Treatments

The eye toxicity is what I get asked the most because it is somewhat unique. You do have to watch some GI, diarrhea or nausea we do use pre-medications. Some people who don't need them but again we try to avoid and be proactive in making sure they do not have nausea and vomiting. It usually isn't again a significant issue. We see some patient at the diarrhea usually low grade every once in a while you'll see a patient with a little bit more pronounced. In the hematologic not usually but you can see it. The warhead is absolutely real. DM4 is a potent anti-microtubule. So you know you have to watch especially with chronic