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The Importance of Recognizing the Unknown Unknowns
There is a very serious body of evidence here. You have an intervention which may not impact people in the way that it should do in the short term. I've spoken to people for the book who are very happily transitioned and they describe puberty blockers as life-saving. The surprising thing is to roll out one intervention to a massive group of people and not think that perhaps something else might be needed in some of those cases.