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#145 – Matthew Johnson: Psychedelics
Lex Fridman Podcast
Psychedelics - Are They a Pitcher or a Catcher?
All of the major psychedelics work by either acting as a pitcher, mimicking a pitcher or a catcher. The classic psychedelics fit into the same catcher's mitt on the post receptor, post synaptic receptor side as serotonin itself. But they do a slightly different thing to the cell to the neuron than serotonin does. There's a different signaling pathway after that initial activation.
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