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In this episode of "Discover Daily," hosts Alex and Sienna explore groundbreaking advancements in medicine, cellular biology, and our understanding of Earth's planetary boundaries.

First, they discuss the FDA's approval of Cobenfy, the first new medication for schizophrenia in over three decades. This novel antipsychotic targets cholinergic receptors in the brain, offering a potentially more effective and tolerable treatment option for the millions of adults living with schizophrenia.

Next, the hosts dive into the discovery of EndoMac progenitors, a new type of cell found in adult mice that can transform into both blood vessel cells and immune cells. These unique cells show remarkable abilities to enhance wound healing, particularly in conditions like diabetes where healing is often impaired. The discovery of EndoMac progenitors, predicted by scientists over a century ago, could open up exciting new avenues for regenerative medicine and tissue repair.

Finally, Alex and Sienna take an in-depth look at the concept of planetary boundaries, the environmental limits within which humanity can safely operate. A recent analysis found that six out of nine of these boundaries have now been crossed, including those for climate change, biodiversity loss, and land-system change. The hosts explain the interconnected nature of these boundaries and discuss the urgent need for transformative action to reduce human impacts on critical Earth systems. They explore the implications for the average person and highlight the importance of understanding these limits for guiding humanity towards a more sustainable future.

From Perplexity's Discover Feed:

https://www.perplexity.ai/page/first-schizophrenia-med-approv-ajWIG4ffQOmbYXfLPl5AjQ

https://www.perplexity.ai/page/new-cell-type-discovered-Tqev0j2pRgao5iqfahpY3g

https://www.perplexity.ai/page/the-nine-planetary-boundaries-JBjdCYnESBeEPa2CiM5Lag

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