Drugs that are small enough to get into the filtrate can then get urinated out. If you have an acid drug like aspirin, if it's exposed to an environment in the urine, that's more basic. It will become ionized and then it can't move. So it gets peed out. But if you have a weak acid like aspirin and the solution is acidic, it remains non-ionized, which means fat soluble. Does it go back into the body? Yeah, I think that also depends on its concentration gradient. And so for the example of aspirin, we seem to like that one today, if you overdose with it as an example, you could give

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