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Self Experiments In the Biochemically Unoptimized State

Mastering Nutrition

CHAPTER

The Effects of Ethanol on Lactate Production

As long as ethanol is in the system, it is serving as a continuous flow of electrons to flip cytosolic NAD+, to NADH. This not only generates lactate, but also prevents the liver from using lactate coming from other tissues. In recreationally active men, 12.1 grams of ethanol from a 40% vodka delivered in two doses, based one hour apart, barely moved lactate at all. It has been known for more than half of a century that ethanol causes blood lactate to go up and decrease its utilization.

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