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How Does Mumps Virus Infect Epithelial Cells?
Mumps virus has a very strong tissue tropism for nervous tissue. It invades and replicates really well in nervous tissue in animal models. In humans, we actually don't see very common neuralogic involvement. The most highly infectious time seems to be that kind of more narrow time window of just before symptoms start and for a few days, maybe up to a week after.