The Importance of Surrogate Endpoints in Trials

There was a lot of chatter online about this sort of hawthorn effect of this trial, like how much was people's behavior changed just by being in this study. Just thinking of my own diet, right? Like, I'm pretty much set with what I eat by this time in my life. And that's often how I look at these trials. But maybe that's the answer here is that we say, listen, what we can learn about these is like, listen, we know some trials which lower blood pressure. These are all surrogate endpoints. They might not be perfect but they may be the best we can do.