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The Mother's Curse Hypothesis
We only get mitochondria from our mum's. That has, from an evolutionary perspective, that has really interesting consequences. The strength of selection depends on population size. As soon as you live inside another cell and you have a small population, then you begin to generate and lose genes. There's about half a million in an oocyte. But what that means is, it's not like having billions of people or billions of bacteria or something. You can no longer have millions and millions of them. In our own cells, we may have a few thousand in an oocytes, in an egg cell. That's as many as we get.