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Gul Dolen on Why Giving MDMA & Psychedelics to Octopuses and Mice Is Important

PSYCHOACTIVE

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MDMA and the Role of Oxytocin in Cognitive Function

There was an idea out there that it might exist, but it wasn't formally demonstrated until we showed it in mice. And when you're administering the MDMA to the mice, does it make a difference whether these mice are the equivalent of juveniles or adolescents or adults? Yeah. So remember at the adult age, the critical period is closed. We gave the MDMA and then we just waited for 48 hours for all of the acute MDMA to wash out of the system. And then we measured social reward learning again in the adult animals. That restoration of the juvenile behavior in adulthood, we thought was very strong evidence that what we've done is reopened this critical period.

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