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Graham Collins, MBBS, on New Agents, Prognostic Models in Hodgkin Lymphoma

The HemOnc Pulse

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Is AAVD Brintoxinab for Neuropathy?

It's really tough with the Echelon data, you know? It absolutely is for advanced stage disease. I think you're limited to very sort of niche groups of patients such as neuropathy. With age normally, they've shown this already, your mutational burden increases. And it again raises the issue that procarbons in particular is pretty damaging and potentially carcinogenic. The other work they're doing now, there was no result presented, but it's fascinating hypothesis: If a patient had three children before having escalated B-COP and then three children afterwards, does it actually affect the germ line?"

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