Challenges and advancements in stem cell technology

The chapter explores the complexities of maintaining self-renewal capacity in stem cell culture systems, focusing on the crucial role of the regulator MCT1 in modulating hematopoietic stem cell function. It also delves into the advancements in iPSC technology for repairing heart damage post-myocardial infarction, the challenges faced in long-term survival of transplants, and the association of genetic mutations like DNMT3A with various health conditions.