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Highlights From the American College of Cardiology’s Scientific Sessions: New Heart Failure Management Guidelines and more

JAMA Medical News

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An interesting study of the role of deltiasm in patients who have what we call a noka or angina with no obstructive coronary disease. VupaNorsen is an angPTL3 inhibitor and has been shown to reduce levels of LDL cholesterol, also levels of triglycerides. Unfortunately there was a significant increase in adverse treatment effects particularly injection site reactions leading to a number of patients discontinuing or having difficulty with therapy. So as a result of that this medication is no longer moving forward as a potential therapy for reducing non-HDL cholesterol.

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