How to Design a Study That Shows Significance

This is part 2 or our 3 part series on microdosing that explore the science, history, and clinical applications. In part 1, we interviewed psychedelic researcher James Fadiman about the fundamentals of microdosing. 

In part 2, we wanted to understand the placebo effect. In particular, is it the microdose that makes people feel better or it is a placebo effect? We interviewed Balázs Szigeti PhD, who is a researcher associate at the Centre for Psychedelic Research at Imperial College London. His team conducted the largest placebo-controlled microdosing study in 2020. Balázs unpacks the study and their findings in the episode.

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Theme music by Dorian Love

Additional Music:
Distant Daze by Zack Frank
Zone Out by Daniel Fridell

Links to topics discussed in this episode:

Self-blinding citizen science to explore psychedelic microdosing (Szigeti et al., 2021)
Centre for Psychedelic Research - Imperial College London
Statistical and clinical significance