Dr. Asaf Hellman: Methylation of DNA, Relationship to Disease
Talking Biotech with Dr. Kevin Folta
00:00
Detection of Methylation
How do you detect methylation? Well metilation is not as easy as regulardin a sequenc but not really complex. The most useful and common way is what we call by sulphi treatment. We treat deine with an chemical that make all see to turn into teas, unless they are metilated. So following this treatment, all nonmetilated te sea will becomete. And by sequence an compared with the original sequence of the dene, can easily deduce what which of the seas was metilated. Also other method, for example, then yo singl molecule sequencs ed the difference between metilated and non metilated es. It's a lot more
Transcript
Play full episode
